Showing posts with label bias. Show all posts
Showing posts with label bias. Show all posts
Sunday, September 1, 2019

Pediatrics and Scare Tactics: From Rock-n-Play to Car Safety Seats

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Is sleeping in a car seat dangerous? Earlier this year, the Fisher-Price company relented to pressure from the AAP (American Academy o...
Thursday, May 17, 2018

Increasing Disparities in Infant Mortality? How a Narrative Can Hinge on the Choice of Absolute and Relative Change

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An April, 11th, 2018 article in the NYT entitled " Why America's Black Mothers and Babies are in a Life-or-Death Crisis " mak...
Saturday, June 11, 2016

Non-inferiority Trials Are Inherently Biased: Here's Why

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Debut VideoCast for the Medical Evidence Blog, explaining non-inferiority trial design and exposing its inherent biases: In this relate...
Monday, May 2, 2016

Hope: The Mother of Bias in Research

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I realized the other day that underlying every slanted report or overly-optimistic interpretation of a trial's results, every contorted...
1 comment:
Wednesday, February 10, 2016

A Focus on Fees: Why I Practice Evidence Based Medicine Like I Invest for Retirement

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He is the best physician who knows the worthlessness of the most medicines."  - Ben Franklin This blog has been highly critical of...
Thursday, February 4, 2016

Diamox Results in Urine: General and Specific Lessons from the DIABOLO Acetazolamide Trial

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The trial of acetazolamide to reduce duration of mechanical ventilation in COPD patients was published in JAMA this week .  I will use ...
4 comments:
Wednesday, July 22, 2015

There is (No) Evidence For That: Epistemic Problems in Evidence Based Medicine

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Below is a Power Point Presentation that I have delivered several times recently including one iteration at the SMACC conference in Chicag...
2 comments:
Thursday, March 20, 2014

Sepsis Bungles: The Lessons of Early Goal Directed Therapy

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On March 18th, the NEJM published early online three original trials of therapies for the critically ill that will serve as fodder for se...
6 comments:
Monday, November 18, 2013

Dead in the Water: Colloids versus Crystalloids for Fluid Resuscitation in the ICU

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It is a valid question:  at what point has a concept been tested ad infinitum such that further testing is not worthwhile?  There are at le...
2 comments:
Thursday, June 20, 2013

More is Not Less, It Just Costs More: Early Tracheostomy, Early Parenteral Nutrition, and Rapid Blood Pressure Lowering in ICH

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The past 2 weeks have provided me with some interesting reading of new data that deserve to be integrated with several other studies and ...
Friday, April 19, 2013

David versus Goliath on the Battlefield of Non-inferiority: Strangeness is in the Eye of the Beholder

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In this week's JAMA is my letter to the editor about the CONSORT statement revision for the reporting of non-inferiority trials, and...
Monday, January 28, 2013

Coffee Drinking, Mortality, and Prespecified Falsification Endpoints

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A few months back, the NEJM published this letter  in response to an article by Freedman et al in the May 17, 2012 NEJM  reporting an ass...
2 comments:
Wednesday, April 8, 2009

The PSA Screening Quagmire - If Ignorance is Bliss then 'Tis Folly to be Wise?

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The March 26th NEJM was a veritable treasure trove of interesting evidence so I can't stop after praising NICE-SUGAR and railing on inte...
3 comments: