Showing posts with label prior probability. Show all posts
Showing posts with label prior probability. Show all posts
Thursday, February 4, 2016

Diamox Results in Urine: General and Specific Lessons from the DIABOLO Acetazolamide Trial

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The trial of acetazolamide to reduce duration of mechanical ventilation in COPD patients was published in JAMA this week .  I will use ...
4 comments:
Saturday, October 11, 2014

Enrolling Bad Patients After Good: Sunk Cost Bias and the Meta-Analytic Futility Stopping Rule

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Four (relatively) large critical care randomized controlled trials were published early in the NEJM in the last week.  I was excited to b...
1 comment:
Sunday, April 6, 2014

Underperforming the Market: Why Researchers are Worse than Professional Stock Pickers and A Way Out

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I was reading in the NYT yesterday a story about Warren Buffet and how the Oracle of Omaha has trailed the S&P 500 for four of the l...
Wednesday, October 24, 2012

A Centrum a Day Keeps the Cancer at Bay?

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Alerted as usual by the lay press to the provocative results of a non-provocative study, I read with interest the article in the Octobe...
3 comments:
Thursday, May 24, 2012

Fever, external cooling, biological precedent, and the epistemology of medical evidence

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It is rare occasion that one article allows me to review so many aspects of the epistemology of medical evidence, but alas Schortgen et a...
1 comment:
Saturday, September 5, 2009

Troponin I, Troponin T, Troponin is the Woe of Me

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As a critical care physician, I have not infrequently been called to the emergency department to admit a patient on the basis of "abnor...
2 comments:
Monday, March 10, 2008

The CORTICUS Trial: Power, Priors, Effect Size, and Regression to the Mean

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The long-awaited results of another trial in critical care were published in a recent NEJM: ( http://content.nejm.org/cgi/content/abstract/3...
4 comments: